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Duggan
Veterinary Supplies
Holycross
Thurles
Co Tipperary
Rep of Ireland
W:+353 (0)504 43169
FAX:+353 (0) 504 43147
E-mail:
info@dugganvet.ie
Drontal
Cats |
|
| PRODUCTS / COMPANION ANIMAL MEDICINE \ DRONTAL CATS | |
| Active |
Praziquantel, Pyrantel embonate |
| Category | Endoparasiticides |
| Target | Cat |
| Web Address: | http://www.noworm.com |
| Mode of Action |  Praziquantel:
Praziquantel kills mature and immature development stages of tapeworms
in the intestine after a single treatment. Within a few seconds of
the tapeworm coming into contact with praziquantel its interaction
with phospholipids and proteins causes damage to the tegument. The
inflow of Ca+2Ions results in an immadiate contraction of the entire
strobila. Moreover, these changes lead to a reduction of glucose intake
and an accelerated depletion of energy reserves. Pyrantel embonate:
Pyrantel, an anthelmintic of the Tetrahydropyrimidine group of compounds,
acts in a similar way to levamisol, by inducing a depolarising neuromuscular
blockade. Pyrantel, being a cholinergic agonist, acts as an excitatory
neurotransmitter at the nicotinergic receptor causing spastic pralysis
of the parasite. |
| Indication/Description | DRONTAL possesses an extremely wide spectrum of activity which covers infestation with the following cat nematodes and cestodes: Nematodes: Ascarids: - Toxocara cati - Toxascaris leonina Hookworms: - Ancylostoma tubaeforme - Ancylostoma braziliense Cestodes: - Echinococcus multilocularis - Dipylidium caninum - Taenia spp. - Joyeuxiella pasqualei - Mesocestoides spp. |
| CAS No | Praziquantel: 55268-74-1 Pyrantel embonate: 22204-24-6 |
| Chemical Name | Praziquantel: 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b
- hexahydro-4H-pyrazino(2,1-a) isoquinolin- 4-one Pyrantel embonate: (E)-1,4,5,6-tetrahydro-1-methyl-2- [2-(2-thienyl) ethenyl] pyrimidine and 4,4'-methylenebis [3-hydroxy-2-naphthalenecarboxylic acid (1:1) |
| Dosage | 1 TABLET PER 4KG |